Publications
This is only a partial publication list. It is arranged based on topics, methods, or specific physiological aspects.
First paper was published in "Israel Journal of Medical Science" in Hebrew. The second in IEEE TBME - both with my Master's thesis advisor, the Late Prof Sid Deutch.
Telemetry System for Stimulation and Monitoring of Freely Moving Patients. IEEE Transactions on BME vol BME-33:3, 1986.
Cardiac assistance and assessment, work that started at Drexel with Dr Dov Jaron and the Late Dr Thomas Moore during my PhD studies and continued at Tel Aviv University
Modeling of cardiovascular dynamics during in-series cardiac assistance. Simulation and Control of the Cardiovascular System vol II, CRC Press, Inc., 1987
Computer Simulation of the Mechanically-Assisted Failing Canine Circulation. Annals of Biomedical Engineering, Vol. 18, pp. 263-283, 1990
Cardiac Energy Considerations During Intra-aortic Balloon Pumping. IEEE Transactions on Biomedical Engineering vol. 37: 2, February 1990
Optimal Control system for the intra-aortic balloon pump. Med & Biol Eng & Comput vol 29 pp 180-184, 1991
Optimal Controller for the intra-aortic balloon pumping. IEEE Transactions on Biomedical Engineering vol. 39: 6, June 1992
Performance Optimization of Left Ventricular Assistance. ASAIO Journal, 39(1), 29-38, 1993
Heart and circulation
Coronary Autoregulation based on energy considerations
Coronary autoregulation and optimal myocardial oxygen utilization. Basic Research in Cardiology 87:290-301, 1992
Mathematical Analysis of Coronary Autoregulation and Vascular Reserve in Closed-Loop Circulation. Computers and Biomedical Research 27, 263-275, 1994
Autoregulation in the Stenosed Coronary Circulation. Comput Biol Med 24:4 pp255-267, 1994
HLHS - Congenital heart malformation
Balancing the Circulation: Theoretic Optimization of Pulmonary/Systemic Flow Ration in Hypoplastic Left Heart Syndrome. JACC 24:5, 1994
Balancing the circulation in hypoplastic left heart syndrome. The Journal of Cardiovascular Surgery 35(6 Suppl 1):137-139, 1994
Theoretical optimization of pulmonary-to-systemic flow
ratio after a bidirectional cavopulmonary anastomosis. Am J Physiol 274(2):H694-700, 1998
Estimation of Oxygen Delivery in Newborns With a Univentricular Circulation. Circulation 98:1407-1413, 1998
Fiber-based models of the contracting heart
A computational method for developing hierarchical large deformation
viscoelastic models of the contracting heart. Computer Methods in Biomechanics and Biomedical Engineering 2010
Multiscale Interactions in a 3D Model of the Contracting Ventricle. Cardiovascular Engineering and Technology 6:4, 2015
Mechano-electric feedback effects in a three dimensional (3D) model of the contracting cardiac ventricle. PLOS ONE 13(1), 2018
Functional assessment of heart and lung - the respiratory work was done with my friend Prof Shimon Abboud
A New Method for the Estimation of the Left Ventricular Pressure-Volume Area. IEEE Transactions on Biomedical Engineering vol. 37: I, January 1990
Intraoperative Monitoring of IMA Flow: What Does it Mean? Ann Thorac Surg 63:S12-7, 1997
Right Atrial Effects on Right Ventricular Ejection Fraction Derived From
Thermodilution Measurements. Journal of Cardiothoracic and Vascular Anesthesia vol 21:5, 2007
Estimation of Forward and Backward Mitral Flow Using Indicator Dilution Technique: A Theoretical Feasibility Study. Cardiovasc Eng 6:161-172, 2006
Maximum Expiratory Flow-Volume Curve: Mathematical Model and Experimental Results. Med Eng Phys 17:5, 1995
New Model-Based Indices for Maximum Expiratory Flow-Volume Curve in Patients with Chronic Obstructive Pulmonary Disease. Comput Biol Med vol 26:2 1996
Model-Based Prediction of Expiratory Resistance Index in Patients with Asthma. Journal of Clinical Monitoring and Computing 18:241-245, 2004
Analysis of non-invasive ventilation effects on gastric inflation using a non-linear mathematical model. Resuscitation 71, 2006
Acoustic Parameters for Optimizing Lung Volume During High-Frequency Oscillatory Ventilation in Infants with Respiratory Distress Syndrome: A Feasibility Study. The Open Medical Devices Journal 2, 2010
Urology and Andrology - bladder and urethral dynamics and penile erection
A Theoretical Unidirectional Valve Based on Functional Collapse of Blood Vessels in the Penis. Annals of Biomedical Engineerin 25, 1997
Hemodynamic Mechanisms of Penile Erection. IEEE Transactions on BME 47:3, 2000
Erection Mechanism of the Penis: a Model Based Analysis. The Journal of Urology 168, 2002
Cavernosometry: a theoretical analysis. International Journal of Impotence Research 16, 2004
A Mathematical Model of Penile Vascular Dysfunction and Its Application to a New Diagnostic Technique. Annals of the NY Academy of Science 1101:439-452, 2007
Model-based estimation of male urethral resistance and
elasticity using pressure-flow data. Computers in Biology and Medicine 31, 2001
Trauma, Fluid Resuscitation, Hemorrhage control
A Computer Model for Analysis of Fluid Resuscitation. Comput Biol Med 23:6, 1993
Myocardial O2 Balance during Fluid Resuscitation in Uncontrolled Hemorrhage: Computer Model. The Journal of Trauma 42:4, 1997
Computer Simulation of Hypothermia during “Damage Control” Laparotomy. World J. Surg. 23, 960–965, 1999
Hemorrhage Control of Liver Injury by Short Electrical Pulses. PLOS ONE 8:1, 2013
Optimization of Oxygen Delivery in Fluid Resuscitation for Hemorrhagic
Shock: A Computer Simulation Study. Cardiovascular Engineering and Technology 5:1, 2013
Blood Flow Versus Hematocrit in Optimization of Oxygen Transfer
to Tissue During Fluid Resuscitation. Cardiovascular Engineering and Technology, 2015
Labor and Fetal Monitoring
The need for a new outlook on labor monitoring. The Journal of Maternal-Fetal and Neonatal Medicine, 19(3), 2006
Continuous monitoring of cervical dilatation and fetal head station during labor. Medical Engineering and Physics 29, 2007
Effects of the individual uterine contraction on fetal head descent and cervical
dilatation during the active stage of labor. European Journal of Obstetrics & Gynecology and Reproductive Biology 2009
Relations Between Fetal Head Descent and Cervical Dilatation During Individual Uterine Contraction in the Active Stage of Labor. The Journal of Obstetrics and Gynaecology Research, 2009
Feto-Maternal Interaction: A Mathematical Model Simulating Placental Response in Hypertensive Disorders of Pregnancy. Reproductive Sciences
17(10), 2010
The role of blood flow distribution in the regulation of cerebral oxygen availability in fetal growth restriction. Medical Engineering & Physics 34, 2012
Reactivity of blood vessels in response to prostaglandin E2 in placentas from pregnancies complicated by fetal growth restriction. Prenatal Diagnosis 32, 2012
Two-dimensional and three-dimensional Doppler assessment of fetal growth restriction with different severity and onset. Prenatal Diagnosis 32, 2012
Inverse Solution of the Fetal-Circulation Model Based on Ultrasound Doppler Measurements. Cardiovascular Engineering and Technology, 5:2, 2014
Labor progress indices and dynamics of the individual uterine contraction during the active stage of labor. J. Obstet. Gynaecol. Res. 40:3, 2014
Intracranial fluids interactions analysis, IntraCranial Elastance and the IntraCranial Assist Device
The Device
Cerebral blood flow augmentation using a cardiac-gated intracranial pulsating balloon pump in a swine model of elevated ICP. J Neurosurg 132:1606–1615, 2020
Cardiac-gated intracranial elastance in a swine model of raised intracranial pressure: a novel method to assess intracranial pressure–volume dynamics. J Neurosurg 134:1650–1657, 2021
Intracranial Pulsating Balloon‑Based Cardiac‑Gated ICP Modulation Impact on Brain Oxygenation: A Proof‑of‑Concept Study in a Swine Model. Neurocrit Care 2022
The Model
Interactions of brain, blood, and CSF: a novel mathematical model of cerebral edema. Fluids Barriers CNS 18:42, 2021
Mechanisms of reduced cerebral blood flow in cerebral edema and elevated ICP, Journal of Applied Physiology, 2022 (accepted)